Inflammation und perioperative vaskuläre Dysfunktion

• Untersuchung der Effekte von Blutprodukten (Erythrozytenkonzentrate, Gefrorenes Frischplasma) auf die endotheliale Funktion
• Untersuchung der Effekte immunsuppressiver Oligonukleotide
• Untersuchung zum Schmerzempfinden und der Narkosetiefe bei Neugeborenen und Kindern bis 2 Jahre bei chirurgischen Eingriffen in Allgemeinanästhesie
• Untersuchung zum Nociception Level Index (NOL) bei Patienten mit tumorchirurgischen Eingriffen im Bereich der HNO und MKG unter Allgemeinanästhesie
• Teilnahme am QUIPS-Register zur Qualitätsverbesserung in der postoperativen Schmerztherapie
• Langzeitoutcome perioperativer Schmerztherapie (LOBSTER-Studie)
• Co-Investigator der POISE-3-Studie (Perioperative Ischemic Evaluation-3 Trial)
• MOPED-Studie (Management and Outcomes of Perioperative Care of European Diabetic Patients)
• USaK-Studie: Präoperativer Ultraschall der Aa. radiales et ulnares als Screening vor geplanter arterieller Katheterisierung
• Untersuchungen zur vaskulären Dysfunktion bei Patientinnen zur zytoreduktiven Operation bei fortgeschrittenem Ovarial-Karzinomen
• Einfluss von zerebralen Flussveränderungen unter extrakorporaler Zirkulation auf die Genese des postoperativen Delirs (The CERBERUS-CODE trial - CEReBral normopERfUSion to COntrol DElirium following cardiac surgery)
• Untersuchungen zum Serumprofil vaskulärer Mediatoren bei der Genese des postoperativen Delirs
• Einfluss von Transfusion auf die zentralveno-arterielle Kohlendioxid-Partialdruck-Differenz

Leitung / Ansprechpartner inkl. Kontaktdaten

PD Dr. Tobias Hilbert und Prof. Dr. Sven Klaschik

• Tel: 0228-287-14114 (Oberarzt-Sekretariat)
• Email: Enable JavaScript to view protected content. und Enable JavaScript to view protected content. 

Weitere wichtige Kooperationspartner und Mitarbeiter

• PD Dr. Stilla Frede
• Dr. Claudia Neumann
• Jennifer Gehlen
• Marcel Scheck

• Dr. Klinman, National Institutes of Health (NIH), USA
• Dr. Per Hoffmann, Institut für Humangenetik/Life & Brain Genomics Bonn
• Prof. Dr. Mustea (Universitäts-Frauenklinik)

Publikationen (Stand 05/2021)

(IF = Impactfaktor des Jahres der Veröffentlichung)

I. Originalarbeiten:

• Menzenbach J, Frede S, Petras J, Guttenthaler V, Kirfel A, Neumann C, Mayr A, Wittmann M, Coburn M, Klaschik S, Hilbert T. Perioperative vascular biomarker profiling in elective surgery patients developing postoperative delirium: a prospective cohort study. Biomedicines 2021 May, 9(5), 553; https://doi.org/10.3390/biomedicines9050553. (IF 4.7)

• Egger EK, Liesenfeld H, Stope MB, Recker F, Döser A, Marinova M, Könsgen D, Hilbert T, Exner D, Ellinger J, Mustea A. Pelvic Exenteration in advanced gynecologic malignancies – who will benefit? Anticancer Res (accepted for publication). (IF 2.0)

• Kinnen A, Klaschik S, Neumann C, Egger E-K, Mustea A, Soehle M, Frede S, Velten M, Coburn M, Hilbert T. Gene expression in the Angiopoietin/TIE axis is altered in peripheral tissue of ovarian cancer patients: A prospective observational study. Life Sci. 2021 Jun 1;274:119345. (IF 3.7)

• Steinhagen F, Hilbert T, Cramer N, Senzig S, Parcina M, Bode C, Boehm O, Frede S, Klaschik S. Development of a minimal invasive and controllable murine model to study polymicrobial abdominal sepsis. Life. 2021 Jan 1;14(1):265–76. (IF 1.3)

• Layer YC, Menzenbach J, Layer YL, Mayr A, Hilbert T, Velten M, Hoeft A, Wittmann M. Validation of the Preoperative Score to Predict Postoperative Mortality (POSPOM) in Germany. PloS One. 2021;16(1):e0245841. (IF 2.74)

• Egger EK, Kohls N, Stope MB, Condic M, Keyver-Paik MD, Könsgen D, Hilbert T, Klaschik S, Exner D, Vilz T, Mustea A. Risk Factors for Severe Complications in Ovarian Cancer Surgery. In Vivo. Nov-Dec 2020;34(6):3361-3365. (IF 1.5)

• Neumann C, Velten M, Heik-Guth C, Strizek B, Wittmann M, Hilbert T, Klaschik S. 5-HT3 blockade does not attenuate postspinal blood pressure change in cesarean section: A case-control study. Medicine (Baltimore). 2020 Sep 4;99(36):e21864. (IF 1.6)

• Hamiko M, Charitos EI, Velten M, Hilbert T, Putensen C, Treede, H, Duerr GD. Mannitol Is Associated with Less Postoperative Delirium after Aortic Valve Surgery in Patients Treated with Bretschneider Cardioplegia. Thorac Cardiovasc Surg. 2020 Sep 4. (IF 1.2)

• Habicht I, Mohsen G, Eichhorn L, Frede S, Weisheit C, Hilbert T, Treede H, Gueresir E, Dewald O, Duerr GD, Velten M. DHA Supplementation Attenuates MI-Induced LV Matrix Remodeling and Dysfunction in Mice. Oxid. Med. Cell. Longev. 2020, 7606938 (2020) (IF 4.9)

• Scheck M, Velten M, Klaschik S, Soehle M, Frede S, Gehlen J, Hoch J, Mustea A, Hoeft A, Hilbert T. Differential Modulation of Endothelial Cell Function by Fresh Frozen Plasma. Life Sci. 2020 May 11;117780. (IF 3.5)

• Gehlen J, Klaschik S, Neumann C, Keyver-Paik MD, Mustea A, Soehle M, Frede S, Velten M, Hoeft A, Hilbert T. Dynamic Changes of Angiopoietins and Endothelial Nitric Oxide Supply During Fluid Resuscitation for Major Gyn-Oncological Surgery: A Prospective Observation. J Transl Med. 2020 Jan;18 (1),48. (IF 4.1)

• Grabert J, Klaschik S, Gueresir Á, Jakobs P, Soehle M, Vatter H, Hilbert T, Gueresir E, Velten M. Supraglottic devices for airway management in awake craniotomy. Medicine (Baltimore). 2019 Oct;98(40):e17473. (IF 1.87)

• Klaschik S, Gehlen J, Neumann C, Keyver-Paik M-D, Soehle M, Frede S, Velten M, Hoeft A, Hilbert T. Network of Mediators for Vascular Inflammation and Leakage Is Dysbalanced during Cytoreductive Surgery for Late-Stage Ovarian Cancer. Mediators Inflamm. 2019;2019:5263717. (IF 3.55)

• Ehrentraut H, Weisheit CK, Frede S, Hilbert T. Inducing Acute Lung Injury in Mice by Direct Intratracheal Lipopolysaccharide Instillation. J Vis Exp JoVE. 2019 Jul 6;(149). (IF 1.11)

• Lorscheidt S, Shetab Boushehri MA, Klaschik S, Lamprecht A.Sub-cytotoxic doses of pharmaceutical silica nanoparticles show significant impact on the proteome of HepG2 cells. J Control Release. 2019 May 23;306:1-14. doi: 10.1016/j.jconrel.2019.05.033. (IF 7,90)

• Tourneur J-M, Weissbrich C, Putensen C, Hilbert T. Feasibility of a protocol to wean patients from continuous renal replacement therapy: A retrospective pilot observation. J Crit Care. 2019 Oct;53:236–43. (IF 2.78)
• Thudium M, Ellerkmann RK, Heinze I, Hilbert T. Relative cerebral hyperperfusion during cardiopulmonary bypass is associated with risk for postoperative delirium: a cross-sectional cohort study. BMC Anesthesiol. 2019 09;19(1):35. (IF 1.62)

• Ehrentraut H, Weisheit C, Scheck M, Frede S, Hilbert T. Experimental murine acute lung injury induces increase of pulmonary TIE2-expressing macrophages. J Inflamm. 2018 Jun 14;15:12. (IF 2.61)

• Hilbert T, Markowski P, Frede S, Boehm O, Knuefermann P, Baumgarten G, Hoeft A, Klaschik S. Synthetic CpG oligonucleotides induce a genetic profile ameliorating murine myocardial I/R injury. J Cell Mol Med. 2018 Jul;22(7):3397–407. (IF 4.30)

• Thudium M, Heinze I, Ellerkmann RK, Hilbert T. Cerebral Function and Perfusion during Cardiopulmonary Bypass: A Plea for a Multimodal Monitoring Approach. Heart Surg Forum. 2018 31;21(1):E028–35. (IF 0.36)

• Hilbert T, Steinhagen F, Senzig S, Cramer N, Bekeredjian-Ding I, Parcina M, Baumgarten G, Hoeft A, Frede S, Boehm O, Klaschik S. Vendor effects on murine gut microbiota influence experimental abdominal sepsis. J Surg Res. 2017 01;211:126–36. (IF 2.05)

• Hilbert T, Dornbusch K, Baumgarten G, Hoeft A, Frede S, Klaschik S. Pulmonary vascular inflammation: effect of TLR signaling on Angiopoietin/TIE regulation. Clin Exp Pharmacol Physiol. 2016 Oct 6. (IF 2.01)

• Hilbert T, Klaschik S, Ellerkmann RK, Putensen C, Thudium M. Common carotid artery diameter responds to intravenous volume expansion: an ultrasound observation. SpringerPlus. 2016;5(1):853. (IF 1.13)

• Hilbert T, Duerr GD, Hamiko M, Frede S, Rogers L, Baumgarten G, Hoeft A, Velten M. Endothelial permeability following coronary artery bypass grafting: an observational study on the possible role of angiopoietin imbalance. Crit Care Lond Engl. 2016;20:51. (IF 5.36)

• Thudium M, Klaschik S, Ellerkmann RK, Putensen C, Hilbert T. Is internal jugular vein extensibility correlated with dynamic indices of fluid responsiveness in ventilated cardiac-surgery patients? Acta Anaesthesiol Scand. 2016;60(6):723-733. (IF 2.44)

• Hilbert T, Ellerkmann RK, Klaschik S, Putensen C, Thudium M. The use of internal jugular vein ultrasound to anticipate low or high central venous pressure during mechanical ventilation. J Emerg Med. 2016;50(4):581-587. (IF 1.21)

• Hilbert T, Steinhagen F, Weisheit C, Baumgarten G, Hoeft A, Klaschik S. Synergistic Stimulation with Different TLR7 Ligands Modulates Gene Expression Patterns in the Human Plasmacytoid Dendritic Cell Line CAL-1. Mediators Inflamm. 2015, Article ID 948540. doi:10.1155/2015/948540 (IF 3.42)

• Klaschik S, Lehmann LE, Steinhagen F, Book M, Molitor E, Hoeft A, Stueber F. Differentiation between Staphylococcus aureus and coagulase-negative staphylococcus species by real-time PCR including detection of methicillin resistants in comparison to conventional microbiology testing. J Clin Lab Anal. 2015 Mar;29(2):122-8. doi: 10.1002/jcla.21739. (IF 1,52)

• Kim S, Becker J, Bechheim M, Kaiser V, Noursadeghi M, Fricker N, Beier E, Klaschik S, Boor P, Hess T, Hofmann A, Holdenrieder S, Wendland JR, Fröhlich H, Hartmann G, Nöthen MM, Müller-Myhsok B, Pütz B, Hornung V, Schumacher J.  Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes.  Nat Commun. 2014 Oct 20;5:5236. doi: 10.1038/ncomms6236. (IF 11,47)

• Hilbert T, Poth J, Frede S, Klaschik S, Hoeft A, Baumgarten G, Knüfermann P. Anti-atherogenic effects of statins: impact on Angiopoietin-2 release from endothelial cells. Biochem Pharmacol. 2013 Nov 15;86(10):1452–60. (IF 4.65)

• Markowski P, Boehm O, Goelz L, Haesner AL, Ehrentraut H, Bauerfeld K, Tran N, Zacharowski K, Weisheit C, Langhoff P, Schwederski M, Hilbert T, Klaschik S, Hoeft A, Baumgarten G, Meyer R, Knuefermann P. Pre-conditioning with synthetic CpG-oligonucleotides attenuates myocardial ischemia/ reperfusion injury via IL-10 up-regulation. Basic Res Cardiol. 2013 Sep;108(5):37 (IF 5.96)

• Hilbert T, Bongartz J, Weisheit C, Knüfermann P, Baumgarten G, Hoeft A, Poth JM. Beta2-Adrenoceptor Stimulation Suppresses TLR9-Dependent IFNA1 Secretion in Human Peripheral Blood Mononuclear Cells. PLoS One. 2013 May 28;8(5):e65024. (IF 3.53)

• Velten M, Duerr GD, Pessies T, Schild J, Lohner R, Mersmann J, Dewald O, Zacharowski K, Klaschik S, Hilbert T, Baumgarten G, Meyer R, Boehm O, Knuefermann P. Priming with Synthetic Oligonucleotides Attenuates Pressure Overload-Induced Inflammation and Cardiac Hypertrophy in Mice. Cardiovasc Res. 2012 Dec 1;96(3):422-32 (IF 5.94)

• Steinhagen F, Meyer C, Tross D, Gursel M, Maeda T, Klaschik S, Klinman DM. Activation of type I interferon-dependent genes characterizes the "core response" induced by CpG DNA. J Leukoc Biol. 2012 Oct;92(4):775-85. (IF 4,57)

• Lehmann LE, Hauser S, Malinka T, Klaschik S, Weber SU, Schewe JC, Stüber F, Book M. Rapid qualitative urinary tract infection pathogen identification by SeptiFast real-time PCR. PLoS One. 2011 Feb 16;6(2):e17146. (IF 4,1)

• Klaschik S, Lehmann LE, Gebel J, Book M, Steinhagen FW, Hoeft A, Stuber F. Species-specific probes and real-time PCR as a tool for fast detection and differentiation of 15 bacteria relevant in intensive care medicine. World J Microbiol Biotechnol. 2011 27:2217–2222 (IF 1,53)

• Klaschik S, Tross D, Shirota H, Klinman DM. Short and long-term changes in gene expression mediated by the activation of TLR9. Mol Immunol. 2010 Mar;47(6):1317-24. (IF 2,92)

• Lehmann LE, Book M, Hartmann W, Weber SU, Schewe JC, Klaschik S, Hoeft A, Stüber F. A MIF haplotype is associated with the outcome of patients with severe sepsis: a case control study. J Transl Med. 2009 Nov 26;7:100. (IF 3,41)

• Lehmann LE, Hauser S, Malinka T, Klaschik S, Stüber F, Book M. Real-time polymerase chain-reaction detection of pathogens is feasible to supplement the diagnostic sequence for urinary tract infections. BJU Int. 2009 Oct 28. (IF 2,87)

• Tross D, Petrenko L, Klaschik S, Zhu Q, Klinman DM. Global changes in gene expression and synergistic interactions induced by TLR9 and TLR3. Mol Immunol. 2009 Aug;46(13):2557-64. (IF 3,20)

• Lehmann LE, Weber SU, Fuchs D, Book M, Klaschik S, Schewe JC, Hoeft A, Stüber F. Oxidoreductase Macrophage Migration Inhibitory Factor is simultaneously increased in leukocyte subsets of patients with severe sepsis. Biofactors. 2008;33(4):281-91. (IF 1,23)

• Klaschik S, Tross D, Klinman DM. Inductive and suppressive networks regulate TLR9- dependent gene expression in vivo. J Leukoc Biol. 2009 May;85(5):788-95. (IF 4,40)

• Weber SU, Schewe JC, Lehmann LE, Müller S, Book M, Klaschik S, Hoeft A, Stüber F. Induction of Bim and Bid gene expression during accelerated apoptosis in severe sepsis. Crit Care. 2008;12(5):R128. (IF 4,55)

• Book M, Chen Q, Lehmann LE, Klaschik S, Weber S, Schewe JC, Luepertz M, Hoeft A, Stuber F. Inducibility of the endogenous antibiotic peptide beta-defensin 2 is impaired in patients with severe sepsis. Crit Care. 2007;11(1):R19. (IF 3,83)

• Klaschik S, Gursel I, Klinman DM. CpG-mediated changes in gene expression in murine spleen cells identified by microarray analysis. Mol Immunol. 2007;44(6): 1095-104. (IF 3,74)

• Schmitz V, Vilanueva H, Raskopf E, Hilbert T, Barajas M, Dzienisowicz C, Gorschlüter M, Strehl J, Rabe C, Sauerbruch T, Prieto J, Caselmann WH, Qian C. Increased VEGF levels induced by anti-VEGF treatment are independent of tumor burden in colorectal carcinomas in mice. Gene Ther. 2006 Aug;13(16):1198-205. (IF 4.78)

• Schmitz V, Kornek M, Hilbert T, Dzienisowicz C, Raskopf E, Rabe C, Sauerbruch T, Qian C, Caselmann WH. Treatment of metastatic colorectal carcinomas by systemic inhibition of vascular endothelial growth factor signaling in mice. World J Gastroenterol. 2005 Jul;11(28):4332-6. (IF 3.32)

• Raskopf E, Dzienisowicz C, Hilbert T, Rabe C, Leifeld L, Wernert N, Sauerbruch T, Prieto J, Qian C, Caselmann WH, Schmitz V. Effective angiostatic treatment in a murine metastatic and orthotopic hepatoma model. Hepatology. 2005 Jun;41(6):1233-40. (IF 9.79)

• Lehmann LE, Weber SU, Fuchs D, Klaschik S, Schewe JC, Book M, Hoeft A, Stuber F. Intracellular detection of macrophage migration inhibitory factor in peripheral blood leukocytes. Free Radic Biol Med. 2005;38(9):1170-9. (IF 4,97)

• Klaschik S, Lehmann LE, Raadts A, Book M, Gebel J, Hoeft A, Stuber F. Detection and differentiation of in vitro-spiked bacteria by real-time PCR and melting-curve analysis. J Clin Microbiol. 2004;42(2):512-7. (IF 3,44)

• Klaschik S, Lehmann LE, Raadts A, Book M, Hoeft A, Stuber F. Real-time PCR for detection and differentiation of gram-positive and gram-negative bacteria. J Clin Microbiol 2002;40(11); 4304-4307 (IF 3,57)

• Klaschik S, Lehmann LE, Raadts A, Hoeft A, Stuber F. Comparison of different decontamination methods for reagents to detect low amounts of bacterial 16s DNA by real-time PCR. Mol Biotechnol 2002;22(3);231-242 (IF 1,0)

• Schroeder S, Lindemann C, Decker D, Klaschik S, Hering R, Putensen C, Hoeft A, Stüber F. Increased susceptibility to apotosis in circulating lymphocytes of critically ill patients. Langenbecks Arch Surg. 2000;386(1):42-46 (IF 1,77)

• Kuhl CK, Milcareck P, Klaschik S, Leutner C, Wardelmann E, Gieseke J, Schild HH. Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions? Radiology.1999;211(1):101-110 (IF 4,62)

• Kuhl CK, Klaschik S, Milcareck P, Gieseke J, Wardelmann E, Schild HH. Do T2-weighted pulse sequences help with the differential diagnosis of enhancing lesions in dynamic breast MRI? J Magn Reson Imaging. 1999;9(2):187-196  (IF 2,41)

II. Fallberichte:

• Thudium M, Kornilov E, Hilbert T, Coburn M, Gestrich C. Extended Neuromonitoring in Aortic Arch Surgery: A Case Series. Anaesthesist. (accepted for publication). (IF 0.9)

• Peukert K, Klaschik S, Hilbert T. Heart rate-dependent ECG changes in a patient with severe sickle cell disease. Anaesthesist. 2021 Mar 16. (IF 0.9)

• Bette B, Martini M, Klaschik S, Hilbert T. Hypoglossal nerve palsy after follicle puncture. Anaesthesist. 2020 Jun; https://doi.org/10.1007/s00101-020-00807-5 (IF 0.9)

• Hilbert T, Boehm O, Pflugmacher R, Wirtz DC, Baumgarten G, Knuefermann P. Rare complication after endoscopic discectomy. Anaesthesist. 2014 Jan;63(1):41-6 (IF 0.76)

III. Übersichtsartikel:

• Hilbert T, Klaschik S. The angiopoietin/TIE receptor system: Focusing its role for ischemia-reperfusion injury. Cytokine Growth Factor Rev. 2015 Jun;26(3):281-91. (IF 6.57)

• Klinman DM, Klaschik S, Tomaru K, Shirota H, Tross D, Ikeuchi H. Immunostimulatory CpG oligonucleotides: Effect on gene expression and utility as vaccine adjuvants. Vaccine. 2010 Feb 23;28(8):1919-23. (IF 3,57)

• Klinman DM, Klaschik S, Tross D, Shirota H, Steinhagen F. FDA guidance on prophylactic DNA vaccines: Analysis and recommendations. Vaccine. 2009 Nov 24. (IF 3,62)

• Klinman DM, Tross D, Klaschik S, Shirota H, Sato T. Therapeutic applications and mechanisms underlying the activity of immunosuppressive oligonucleotides. Ann N Y Acad Sci. 2009 Sep;1175:80-8. Review. (IF 2,67)

• Klinman DM, Klaschik S, Sato T, Tross D. CpG oligonucleotides as adjuvants for vaccines targeting infectious diseases. Adv Drug Deliv Rev. 2009 Mar 28;61(3):248-55. Review. (IF 11,96)

• Klinman DM, Shirota H, Tross D, Sato T, Klaschik S. Synthetic oligonucleotides (ODN) as modulators of inflammation. J Leukoc Biol. 2009;85(5):788-795. (IF 4,4)

• Klinman DM, Gursel I, Klaschik S, Dong L, Currie D, Shirota H. Therapeutic potential of oligonucleotides expressing immunosuppressive TTAGGG motifs. Ann N Y Acad Sci. 2005;1058:87-95. (IF 1,97)

• Stuber F, Klaschik S, Lehmann LE, Schewe JC, Weber S, Book M. Cytokine promoter polymorphisms in severe sepsis. Clin Infect Dis. 2005;41 Suppl 7:S416-20.
  (IF 6,51)

• Stuber F, Book M, Klaschik S, Lehmann LE, Schewe JC, Hoeft A, Stamer U. Bedeutung der Genetik fuer die Anaesthesiologie. Anaesthesiologie & Intensivmedizin 2004:45:415-428. (IF 0,5)

IV. Letters:

• Hilbert T. Video laryngoscopy during airway management in COVID-19 patients: practical relevance of a recent EJA Christmas issue article. Eur J Anaesthesiol 2021 Jan;38(1):98-99. (IF 4.5)

• Kirchertz R, Hilbert T. A week of slow hearts: anaesthesia for eye surgery and shortage of glycopyrrolate. Minerva Anestesiol. 2019 Sep;85(9):1033–4. (IF 2.84)

• Hilbert T, Weber S, Knies R, Kim S-C. Value of ultrasound with a single linear transducer to confirm correct positioning of central venous catheter in low body weight neonates. Eur J Anaesthesiol. 2015;32(12):893-894. (IF 3.63)

V. Buchbeiträge:

• Zacharowski K, Marx G. Referenz Anästhesie. (2020) Stuttgart, Georg Thieme Verlag KG

• Klinman DM and Klaschik S. Modulation of Regulation of Gene Expression by CpG Oligonucleotdies. Chapter 11 in “Nucleic Acids and Molecular Biology”, Eds: Kikuchi T and Ryokova E. Springer-Verlag Berlin 2010, Volume 25, 191-208

• 2002: DIVI (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin) Poster-Preis für: “Grampositiv/Gramnegativ-Schnelldifferenzierung intensivmedizinisch relevanter Keime mittels Echtzeit-Polymerasekettenreaktion“

• 2003: SCCM (Society of Critical Care Medicine): “Educational Scholarship Award”: “Real-time PCR and melting curve analysis for fast species-specific differentiation of bacterial DNA from intensive care unit relevant species”

• 2004: SCCM (Society of Critical Care Medicine) “Young Investigator Award”: “Species specific probes and real-time PCR as a tool for fast detection and differentiation of bacteria relevant in intensive care”

• 2008: ISICR (International Society for Interferon and Cytokine Research): "Seymour and Vivian Milstein Poster Award": "Inductive and suppressive networks regulated TLR9-dependent gene expression in vivo" 2015 Hauptstadtkongress der DGAI: Poster-Preis für: “Variationen in der bakteriellen Stuhlzusammensetzung von C57BL/6-Mäusen verschiedener Lieferanten und Bezugszeiträume“

• 2015: Hauptstadtkongress der DGAI: Vortragspreis für: “Endotheliale Hyperpermeabilität nach extrakorporaler Zirkulation: Rolle der Angiopoietin-2/-1- Balance“

• 2017: Herbsttreffen des Wissenschaftlichen Arbeitskreises Kardioanästhesie der DGAI: Poster-Preis für: “Eine relative zerebrale Hyperperfusion während extrakorporaler Zirkulation ist bei kardiochirurgischen Patienten mit der Entwicklung eines postoperativen Delirs assoziiert“

• 2019: Hauptstadtkongress der DGAI: Poster-Preis für: “Zytoreduktive Chirurgie beim fortgeschrittenen Ovarial-Karzinom führt zu Dysregulationen innerhalb eines interaktiven Netzwerks proinflammatorischer und barriereaktiver Mediatoren“

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