The group’s research focuses on the etiology and preclinical detection of eye diseases, including age-related macular degeneration, diabetic retinopathy, glaucoma, and keratoconus. By integrating clinical expertise with molecular deep phenotyping, genetic epidemiology and advanced high-resolution imaging of the eye and brain the group aims to characterize early structural and molecular alterations along the pathophysiological continuum of ocular disease. A central goal is to establish a biologically grounded framework for precision patient stratification and the development of targeted therapeutic strategies.
Dr Larsen is a clinician-scientist and ophthalmologist at the University Eye Hospital Bonn and the German Center for Neurodegenerative Diseases. She studied medicine at Heidelberg University and completed research training at the University of Chicago and the Université de Bordeaux, where she also obtained her PhD and completed postdoctoral training. At the German Center for Neurodegenerative Diseases, Dr Larsen leads the ophthalmologic section of the Rhineland Study, an ongoing prospective cohort study with more than 15,000 participants currently enrolled.
Studium der Humanmedizin an der Universität Tübingen und Freien Universität Berlin und Studium der Humanbiologie an der Ecole Normale Supérieure (Paris).
1998 PhD at the Department of Ophthalmology, Eberhard Karls University of Tübingen
2006 Habilitation and venia legendi in ophthalmology, University of Bonn
1996–2002 Specialist training at the University Eye Clinic in Heidelberg
2002 Recognition as a specialist
2002 Fellow of the European Board of Ophthalmology
2002–2004 Senior Registrar in the Department of Paediatric Ophthalmology, Strabismus and Ophthalmogenetics, University of Regensburg (Head: Prof. Dr B. Lorenz)
Since 2004 Senior Registrar in the Department of Orthoptics, Neuro- and Paediatric Ophthalmology at the University Eye Clinic, Bonn (Prof. Dr F. Holz),
since 2007 Head of the Department of Orthoptics, Neuro- and Paediatric Ophthalmology and the State Training Centre for Orthoptists at the University Eye Clinic, Bonn
