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Degenerative retinal diseases

Prof. Dr. Volker Busskamp

Prof. Dr. Volker Busskamp

In order to understand how parts of the human brain, especially the retina, function in health and disease, we perform an interdisciplinary and integrative approach combining stem cell research, systems biology, bioengineering, biomedicine with visual neuroscience. Our ultimate goal is to develop innovative therapies to protect, preserve and restore visual functions.

Education
  • 2007 – 2010: PhD in Neuroscience, Friedrich Miescher Institute and University of Basel, Switzerland (Botond Roska)
  • 2006 - 2007: Post graduate diploma in Biology (DEA), University of Geneva, Switzerland
  • 2001 – 2006: Diploma in Biotechnology, Technical University of Braunschweig, Germany
 Positions held 
  • Since 2019: Professor for degenerative retinal diseases, Department of Ophthalmology, University of Bonn, Germany
  • Since 2014: Research Group Leader and Freigeist Fellow at the Center for Regenerative Therapies Dresden (CRTD), Germany 
  • 2011 – 2014: Postdoctoral fellow, Harvard Medical School, Boston, USA (George M. Church)
  • 2010 – 2011: Postdoctoral fellow, Friedrich Miescher Institute, Basel, Switzerland (Botond Roska)
Training
  • 2014/2015: by the Volkswagen Foundation and Zentrum für Wissenschaftsmanagement e.V.

Dr. Kirsten Harmening (Lab Manager)

Dr. Sarah Kunze (Lab Coordinator)

Dr. Rouhollah Habibey (Postdoc)

Marta Zuzic (Scientist)

Julia Pawlick (PhD student)

Kritika Sharma (PhD student)

Johannes Striebel (PhD student)

Giovanni Pasquini (PhD student)

Elizaveta Podoliak (PhD student)

Mareike Eis (WHF)

Sijia Yan (Medical student)

Marie Igelbüscher (Master student)

  • Gabriel E, Albanna W, Pasquini G, Ramani A, Josipovic N, Mariappan A, Schinzel F, Karch CM, Bao G, Gottardo M, Suren AA, Hescheler J, Nagel-Wolfrum K, Persico V, Rizzoli SO, Altmüller J, Riparbelli MG, Callaini G, Goureau O, Papantonis A, Busskamp V, Schneider T, Gopalakrishnan J. Human brain organoids assemble functionally integrated bilateral optic vesicles. Cell Stem Cell. 2021 Aug 12:S1934-5909(21)00295-2. doi: 10.1016/j.stem.2021.07.010. Epub ahead of print. PMID: 34407456.
  • Kutsche L, Gysi DM, Fallmann J, Lenk K, Petri R, Swiersy A, Klapper SD, Pircs K, Khattak S, Stadler PF, Jakobsson J, Nowick K, Busskamp V. “Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis”, Cell Systems 2018 Oct 3.
  • Busskamp V, Lewis NE, Guye P, Ng AHM, Shipman SL, Byrne SE, Murn J, Sanjana NE, Li S, Li Y, Stadler M, Weiss R, Church GM. “Rapid neurogenesis through transcriptional activation in human stem cells”, Molecular Systems Biology 2014 Nov 17.
  • Busskamp V, Krol J, Nelidova D, Daum J, Szikra T, Tsuda B, Jüttner J, Farrow K, Gross Scherf B, Patino Alvarez CP, Genoud C, Sothilingam V, Tanimoto N, Stadler M, Seeliger M, Stoffel M, Filipowicz M, Roska. “MicroRNAs 182 and 183 are necessary to maintain adult cone photoreceptor outer segments and visual function”, Neuron 2014 Aug 6.
  • Busskamp V, Duebel J, Balya D, Fradot M, Viney TJ, Siegert S, Groner AC, Cabuy E, Forster V, Seeliger M, Biel M, Humphries P, Paques M, Mohand-Said S, Trono D, Deisseroth K, Sahel JA, Picaud S, Roska B. ”Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis pigmentosa”, Science. 23 July 2010.

more publications

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