Degenerative Netzhauterkrankungen
Prof. Dr. Volker Busskamp
Unsere Forschung fokussiert sich darauf, wie bestimmte Teile des Gehirns, vor allem die Retina, funktionieren. Wir untersuchen ihre Funktionen sowohl im gesunden als auch im erkrankten Zustand, wofür wir verschiedene Forschungsbereiche vereinen: Stammzellforschung, Systembiologie, Biotechnologie, Biomedizin und visuelle Neurowissenschaften. Unser Ziel ist es innovative Therapien zu entwickeln, um das Sehvermögen zu schützen, zu erhalten und wiederherzustellen.
Education
- 2007 – 2010: PhD in Neuroscience, Friedrich Miescher Institute and University of Basel, Switzerland (Botond Roska)
- 2006 - 2007: Post graduate diploma in Biology (DEA), University of Geneva, Switzerland
- 2001 – 2006: Diploma in Biotechnology, Technical University of Braunschweig, Germany
Positions held
- Since 2019: Professor for degenerative retinal diseases, Department of Ophthalmology, University of Bonn, Germany
- 2014 – 2021: Research Group Leader and Freigeist Fellow at the Center for Regenerative Therapies Dresden (CRTD), Germany
- 2011 – 2014: Postdoctoral fellow, Harvard Medical School, Boston, USA (George M. Church)
- 2010 – 2011: Postdoctoral fellow, Friedrich Miescher Institute, Basel, Switzerland (Botond Roska)
Training
- 2014/2015: by the Volkswagen Foundation and Zentrum für Wissenschaftsmanagement e.V.
Dr. Kirsten Harmening (Lab Manager)
Dr. Sarah Kunze (Lab Coordinator)
Dr. Rouhollah Habibey (Postdoc)
Dr. Robert Prior (Postdoc)
Julia Pawlick (Doktorandin)
Kritika Sharma (Doktorandin)
Johannes Striebel (Doktorand)
Elizaveta Podoliak (Doktorandin)
Sarah Schunk (Doktorandin)
Jasmin Zorn (SHK)
Jana Böhringer (SHK)
- Ng, A. H., Khoshakhlagh, P., Arias, J. E. R., Pasquini, G., Wang, K., Swiersy, A., ... Busskamp, V. * & Church, G. M. * (2021). A comprehensive library of human transcription factors for cell fate engineering. Nature biotechnology, 39(4), 510-519. * authos share correspondence
- Gabriel E, Albanna W, Pasquini G, Ramani A, Josipovic N, Mariappan A, Schinzel F, Karch CM, Bao G, Gottardo M, Suren AA, Hescheler J, Nagel-Wolfrum K, Persico V, Rizzoli SO, Altmüller J, Riparbelli MG, Callaini G, Goureau O, Papantonis A, Busskamp V, Schneider T, Gopalakrishnan J. Human brain organoids assemble functionally integrated bilateral optic vesicles. Cell Stem Cell. 2021 Aug 12:S1934-5909(21)00295-2.
- Kutsche L, Gysi DM, Fallmann J, Lenk K, Petri R, Swiersy A, Klapper SD, Pircs K, Khattak S, Stadler PF, Jakobsson J, Nowick K, Busskamp V. “Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis”, Cell Systems 2018 Oct 3.
- Busskamp V, Lewis NE, Guye P, Ng AHM, Shipman SL, Byrne SE, Murn J, Sanjana NE, Li S, Li Y, Stadler M, Weiss R, Church GM. “Rapid neurogenesis through transcriptional activation in human stem cells”, Molecular Systems Biology 2014 Nov 17.
- Busskamp V, Krol J, Nelidova D, Daum J, Szikra T, Tsuda B, Jüttner J, Farrow K, Gross Scherf B, Patino Alvarez CP, Genoud C, Sothilingam V, Tanimoto N, Stadler M, Seeliger M, Stoffel M, Filipowicz M, Roska. “MicroRNAs 182 and 183 are necessary to maintain adult cone photoreceptor outer segments and visual function”, Neuron 2014 Aug 6.
- Busskamp V, Duebel J, Balya D, Fradot M, Viney TJ, Siegert S, Groner AC, Cabuy E, Forster V, Seeliger M, Biel M, Humphries P, Paques M, Mohand-Said S, Trono D, Deisseroth K, Sahel JA, Picaud S, Roska B. ”Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis pigmentosa”, Science. 23 July 2010.
