Publications Jun. Prof. Kerstin Wilhelm-Jüngling

Ong YT, Andrade J, Armbruster M, Shi Ch, Castro M, Costa A, Toshiya S, Eelen G, Zimmermann B, Wilhelm K, Lim J, Watanabe S, Guenther S, Schneider A, Zanconato F, Kaulich M, Pan D, Braun T, Gerhardt H, Efeyan A, Carmeliet P, Piccolo S, Grosso AR, Potente M. A YAP/TAZ-TEAD signaling module links endothelial nutrient acquisition to angiogenic growth. Nat Met. 2022, 4,672– 682.  https://www.nature.com/articles/s42255-022-00584-y

Andrade J, Shi Ch, Costa ASH, Choi J, Kim J, Doddaballapur A, Sugino T, Ong YT, Castro M, Zimmermann B, Kaulich M, Guenther S, Wilhelm K, Kubota Y, Braun T, Koh GY, Grosso AR, Frezza Ch, Potente M. Control of endothelial quiescence by FOXO-regulated metabolites. Nat Cell Biol. 2021, 23, 413–423. https://www.nature.com/articles/s41556-021-00637-6

Chatterjee A, Eshwaran R, Poschet G, Lomada S, Halawa M, Wilhelm K, Schmidt M, Hammes HP, Wieland T, Feng Y. Involvement of NDPK-B in glucose metabolism-mediated endothelial damage via activation of the hexosamine biosynthesis pathway and suppression of O-GlcNAcase activity. Cells 2020, 9(10), 2324. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7588982/

Helker CSM, Eberlein J, Wilhelm K, Sugino T, Malchow J, Schuermann A, Baumeister S, Kwon HB, Maischein HM, Potente M, Herzog W, Stanier DYR. Apelin drives vascular endothelial cells towards a pro-angiogenic stage. elife. 2020;9:e55589. https://elifesciences.org/articles/55589

Lim R, Sugino T, Nolte H, Andrade J, Zimmermann B, Shi C, Doddaballapur A, Ong YT, Wilhelm K, Fasse JWD, Ernst A, Kaulich M, Husnjak K, Boettger T, Guenther S, Braun T, Krüger M, Benedito R, Dikic I, Potente M. Deubiquitinase USP10 regulates Notch signaling in the endothelium. Science. 2019 Apr 12; 364(6436):188-193. https://www.science.org/doi/10.1126/science.aat0778

Stubendorff B, Wilhelm K, Posselt K, Catto J, Hartmann A, Bertz S, Füssel S, Novotny V, Toma M, Gajda M, Lehmann J, Wunderlich H, Grimm MO, Stöckle M, Junker K. A three-gene methylation marker panel for the nodal metastatic risk assessment of muscle-invasive bladder cancer. J Cancer Res Clin Oncol. 2019 Apr;145(4):811-820. https://link.springer.com/article/10.1007/s00432-018-02829-4

Stone OA, El-Brolosy M, Wilhelm K, Liu X, Romão AM, Grillo E, Lai JKH, Günther S, Jeratsch S, Kuenne C, Lee IC, Braun T, Santoro MM, Locasale JW, Potente M, Stainier DYR. Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells. Nat Commun. 2018 Oct 9;9(1):4077. https://www.nature.com/articles/s41467-018-06406-8

Yu P, Wilhelm K, Dubrac A, Tung JK, Alves TC, Fang JS, Xie Y, Zhu J, Chen Z, De Smet F, Zhang J, Jin SW, Sun L, Sun H, Kibbey RG, Hirschi KK, Hay N, Carmeliet P, Chittenden TW, Eichmann A, Potente M, Simons M. FGF-dependent metabolic control of vascular development. Nature. 2017 May 11;545(7653):224-228. https://www.nature.com/articles/nature22322

Wilhelm K, Potente M. Metabolische Regulation des Blutgefäßwachstums. Biospektrum. 2016

Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich MF, Lim R, Zimmermann B, Aspalter IM, Franco CA, Boettger T, Braun T, Fruttiger M, Rajewsky K, Keller C, Brüning JC, Gerhardt H, Carmeliet P, Potente M. FOXO1 couples metabolic activity and growth state in the vascular endothelium. Nature. 2016 Jan 14;529(7585):216-20.. https://www.nature.com/articles/nature16498