Laboratory Research
Tonabersat enhances temozolomide-mediated cytotoxicity in glioblastoma by disrupting intercellular connectivity through connexin 43 inhibition
Elena N. C. Schmidt*, Bernd O. Evert*, Barbara E. F. Pregler, Ahmad Melhem, Meng-Chun Hsieh, Markus Raspe, Hannah Strobel, Julian Roos, Torsten Pietsch, Patrick Schuss, Pamela Fischer-Posovszky, Mike-Andrew Westhoff, Michael Hölzel, Ulrich Herrlinger, Hartmut Vatter, Andreas Waha, Matthias Schneider, Anna-Laura Potthoff; * shared first authorship
Molecular Oncology, 2024
Gene expression signature-defined necroinflammation is not associated with sex-biased survival or bevacizumab benefit in glioblastoma
Johannes Weller, Emre Kocakavuk, Barbara E. F. Pregler, Thomas Zeyen, Niklas Schäfer, Anna-Laura Potthoff, Matthias Schneider, Ulrich Herrlinger
Neuro-Oncology, 2024
The Alcatraz-Strategy: a roadmap to break the connectivity barrier in malignant brain tumors
Matthias Schneider, Anna-Laura Potthoff, Georg Karpel-Massler, Patrick Schuss, Markus D Siegelin, Klaus-Michael Debatin, Hugues Duffau, Hartmut Vatter, Ulrich Herrlinger, Mike-Andrew Westhoff
Molecular Oncology, 2024
Downregulation of MGMT expression by targeted editing of DNA methylation enhances temozolomide sensitivity in glioblastoma
Xinyu Han, Mohammed O E Abdallah, Peter Breuer, Fabian Stahl, Yousuf Bakhit, Anna-Laura Potthoff, Barbara E F Pregler, Matthias Schneider, Andreas Waha, Ulrich Wüllner ‡, Bernd O Evert ‡; ‡ shared senior authorship
Neoplasia, 2023
Disconnecting multicellular networks in brain tumours
Varun Venkataramani*, Matthias Schneider*, Frank Anton Giordano, Thomas Kuner, Wolfgang Wick, Ulrich Herrlinger‡, Frank Winkler‡; * shared first authorship, ‡ shared senior authorship
Nature Reviews Cancer, 2022
Phase I/II trial of meclofenamate in progressive MGMT-methylated glioblastoma under temozolomide second-line therapy-the MecMeth/NOA-24 trial
Thomas Zeyen*, Anna-Laura Potthoff*, Robert Nemeth, Dieter H. Heiland, Michael C. Burger, Joachim P. Steinbach, Peter Hau, Ghazaleh Tabatabai, Martin Glas, Uwe Schlegel, Oliver Grauer, Dietmar Krex, Oliver Schnell, Roland Goldbrunner, Michael Sabel, Niklas Thon, Daniel Delev, Hans Clusmann, Clemens Seidel, Erdem Güresir, Matthias Schmid, Patrick Schuss, Frank A. Giordano, Alexander Radbruch, Albert Becker, Johannes Weller, Christina Schaub, Hartmut Vatter, Judith Schilling, Frank Winkler, Ulrich Herrlinger, Matthias Schneider; * shared first authorship,
Trials, 2022
Meclofenamate causes loss of cellular tethering and decoupling of functional networks in glioblastoma
Matthias Schneider*, Lea Vollmer*, Anna-Laura Potthoff*, Vidhya M Ravi, Bernd O Evert, Mohummad A Rahman, Shahin Sarowar, Jan Kueckelhaus, Paulina Will, David Zurhorst, Kevin Joseph, Julian P Maier, Nicolas Neidert, Paolo d'Errico, Melanie Meyer-Luehmann, Ulrich G Hoffmann, Andreas Dolf, Paolo Salomoni, Erdem Güresir, Per O Enger, Martha Chekenya, Torsten Pietsch, Patrick Schuss, Oliver Schnell, Mike-Andrew Westhoff, Jürgen Beck, Hartmut Vatter, Andreas Waha, Ulrich Herrlinger ‡, Dieter H Heiland ‡; * shared first authorship, ‡ shared senior authorship
Neuro-Oncology, 2021
Inhibition of Intercellular Cytosolic Traffic via Gap Junctions Reinforces Lomustine-Induced Toxicity in Glioblastoma Independent of MGMT Promoter Methylation Status
Matthias Schneider, Anna-Laura Potthoff, Bernd O Evert, Marius Dicks, Denise Ehrentraut, Andreas Dolf, Elena N C Schmidt, Niklas Schäfer, Valeri Borger, Torsten Pietsch, Mike-Andrew Westhoff, Erdem Güresir, Andreas Waha, Hartmut Vetter, Dieter H Heiland, Patrick Schuss ‡, Ulrich Herrlinger ‡, ‡ shared senior authorship
Pharmaceuticals, 2021
Inhibition of Gap Junctions Sensitizes Primary Glioblastoma Cells for Temozolomide
Anna-Laura Potthoff, Dieter Henrik Heiland, Bernd O. Evert, Filipe Rodrigues Almeida, Simon P. Behringer, Andreas Dolf, Ági Güresir, Erdem Güresir, Kevin Joseph, Torsten Pietsch, Patrick Schuss, Ulrich Herrlinger, Mike-Andrew Westhoff, Hartmut Vatter, Andreas Waha, Matthias Schneider
Cancers, 2019
Gliomatosis cerebri: no evidence for a separate brain tumor entity
Ulrich Herrlinger, David T W Jones, Martin Glas, Elke Hattingen, Dorothee Gramatzki, Moritz Stuplich, Jörg Felsberg, Oliver Bähr, Gerrit H Gielen, Matthias Simon, Dorothee Wiewrodt, Martin Schabet, Volker Hovestadt, David Capper, Joachim P Steinbach, Andreas von Deimling, Peter Lichter, Stefan M Pfister, Michael Weller, Guido Reifenberger
Acta Neuropathologica, 2015
A paired comparison between glioblastoma “stem cells” and differentiated cells
Matthias Schneider, Stephanie Ströbele, Lisa Nonnenmacher, Markus D. Siegelin, Melanie Tepper, Sebastien Stroh, Sebastian Hasslacher, Stefanie Enzenmüller, Gudrun Strauss, Bernd Baumann, Georg Karpel-Massler, Mike-Andrew Westhoff, Klaus-Michael Debatin, Marc-Eric Halatsch
International Journal of Cancer, 2015
