Menu

Publikationen

2012

Aronica E, Becker AJ, Spreafico R. Malformations of cortical development. Brain Pathology, 22(3):380-401, 2012.

Berson A, Barbash S, Shaltiel G, Goll Y, Hanin G, Greenberg DS, Ketzef M, Becker AJ, Friedman A, Soreq H. Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice. EMBO Mol Med, 4(8):730-742, 2012.

Bien CG, Raabe AL, Schramm J, Becker A, Urbach H, Elger CE. Trends in presurgical evaluation and surgical treatment of epilepsy at one centre from 1988-2009. J Neurol Neurosurg Psychiatry. 2012 Oct 10. [Epub ahead of print]

Bien CG, Vincent A, Barnett MH, Becker AJ, Blümcke I, Graus F, Jellinger KA, Reuss DE, Ribalta T, Schlegel J, Sutton I, Lassmann H, Bauer J. Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis. Brain, 135(Pt 5):1622-1638, 2012.

Ekstein D, Benninger F, Daninos M, Pitsch J, van Loo KM, Becker AJ, Yaari Y. Zinc induces long-term upregulation of T-type calcium current in hippocampal neurons in vivo. J Physiol, 590:5895-5905, 2012.

Raabe A, Schmitz AK, Pernhorst K, Grote A, von der Brelie C, Urbach H, Friedman A, Becker AJ, Elger CE, Niehusmann P. Clinico-neuropathological correlations show astroglial albumin storage as common factor in epileptogenic vascular lesions. Epilepsia, 53(3):539-548, 2012.

Coras R, de Boer OJ, Armstrong D, Becker A, Jacques TS, Miyata H, Thom M, Vinters HV, Spreafico R, Oz B, Marucci G, Pimentel J, Mühlebner A, Zamecnik J, Buccoliero AM, Rogerio F, Streichenberger N, Arai N, Bugiani M, Vogelgesang S, Macaulay R, Salon C, Hans V, Polivka M, Giangaspero F, Fauziah D, Kim JH, Liu L, Dandan W, Gao J, Lindeboom B, Blümcke I, Aronica E. Good interobserver and intraobserver agreement in the evaluation of the new ILAE classification of focal cortical dysplasias. Epilepsia, 53(8):1341-1348, 2012.

Gousias K, Becker AJ, Simon M, Niehusmann P. Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas. J Neurooncol, 109(3):545-553, 2012.

Marcelin B, Lugo JN, Brewster AL, Liu Z, Lewis AS, McClelland S, Chetkovich DM, Baram TZ, Anderson AE, Becker A, Esclapez M, Bernard C. Differential dorso-ventral distributions of Kv4.2 and HCN proteins confer distinct integrative properties to hippocampal CA1 pyramidal cell distal dendrites. J Biol Chem, 287(21):17656-17661, 2012.

Marcelin B, Liu Z, Chen Y, Lewis AS, Becker A, McClelland S, Chetkovich DM, Migliore M, Baram TZ, Esclapez M, Bernard C. Dorsal-ventral differences in intrinsic properties in developing CA1 pyramidal cells. J Neurosci, 32(11):3736-3747, 2012.

Müller T, Gessi M, Waha A, Isselstein LJ, Luxen D, Freihoff D, Freihoff J, Becker A, Simon M, Hammes J, Denkhaus D, Zur Mühlen A, Pietsch T, Waha A. Nuclear exclusion of TET1 is associated with loss of 5-hydroxymethylcytosine in IDH1 wild-type gliomas. Am J Pathol, 181(2):675-83, 2012.

Van Loo KM, Schaub C, Pernhorst K, Yaari Y, Beck H, Schoch S, Becker AJ. Transcriptional regulation of T-type calcium channel CaV3.2: bi-directionality by early growth response 1 (Egr1) and repressor element 1 (RE-1) protein-silencing transcription factor (REST). J Biol Chem, 287(19):15489-501, 2012.

2011

Albayram O, Alferink J, Pitsch J, Piyanova A, Neitzert K, Poppensieker K, Mauer D, Michel K, Legler A, Becker A, Monory K, Lutz B, Zimmer A, Bilkei-Gorzo A. Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging. Proc Natl Acad Sci USA, 108(27):11256-11261, 2011.

Becker SJ, Matusch A, Becker JS, Wu B, Palm C, Becker AJ, Salber D. Mass Spectrometric Imaging (MSI) of metals for biomedical research. Int J Mass Spectrom, 307(1-3):3-15, 2011.

Blümcke, I, Thom M, Aronica E, Armstrong DD, Vinters HV, Palmini A, Jacques TS, Avanzini G, Barkovich AJ, Battaglia G, Becker A, Cepeda C, Cendes F, Colombo N, Crino P, Cross JH, Delalande O, Dubeau F, Duncan J, Guerrini R, Kahane P, Mathern G, Najm I, Özkara C, Raybaud C, Represa A, Roper SN, Salamon N, Schulze-Bonhage A, Tassi L, Vezzani A, Spreafico R. The clinico-pathological spectrum of Focal Cortical Dysplasias: a consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission. Epilepsia, 52(1):158-174, 2011.

Jung S, Warner LN, Pitsch J, Becker AJ, Poolos NP. Rapid loss of dendritic HCN channel expression in hippocampal pyramidal neurons following status epilepticus. J Neurosci. 31(40):14291-14295, 2011.

Ketzef M, Kahn J, Weissberg I, Becker AJ, Friedman A, Gitler D. Compensatory network alterations upon onset of epilepsy in synapsin triple knock-out mice. Neuroscience, 189:108-122, 2011.

Kohli MA, Lucae S, Saemann PG, Schmidt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, Wolf C, Ising M, Schreiber S, Czisch M, Müller MB, Uhr M, Bettecken T, Becker A, Schramm J, Rietschel M, Maier W, Bradley B, Ressler KJ, Nöthen MM, Cichon S, Craig IW, Breen G, Lewis CM, Hofman A, Tiemeier H, van Duijn CM, Holsboer F, Müller-Myhsok B, Binder EB. The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron, 70(2):252-265, 2011.

Pernhorst K, Raabe A, Niehusmann P, van Loo KMJ, Grote A, Hoffmann P, Cichon S, Sander T, Schoch S, Becker AJ. Promoter variants determine GABA-homeostasis related gene transcription in human epileptic hippocampi. J Neuropathol Exp Neurol, 70(12):1080-1088, 2011.

Schijns OE, Bien CG, Majores M, von Lehe M, Urbach H, Becker A, Schramm J, Elger CE, Clusmann H. Presence of temporal gray-white matter abnormalities does not influence epilepsy surgery outcome in temporal lobe epilepsy with hippocampal sclerosis. Neurosurgery, 68(1):98-106, 2011.

Schönberger A, Gembe E, Grote A, Witt JA, Elger CE, Bien CG, Urbach H, Becker AJ, Niehusmann P. Genetic analysis of tuberous-sclerosis genes 1 and 2 in non-lesional focal epilepsy. Epilepsy Behav, 21(3):233-237, 2011.

Wilcke A, Ligges C, Burkhardt J, Alexander M, Wolf C, Quente E, Ahnert P, Hoffmann P, Becker A, Müller-Myhsok B, Cichon S, Boltze J, Kirsten H. Imaging genetics of FOXP2 in dyslexia. Eur J Hum Genet, in press, 2011.

Zürner M, Mittelstaedt T, tom Dieck S, Becker AJ, Schoch S. Differential spatiotemporal expression and subcellular localization of Liprin-a proteins indicate isoform specific functions. J Comp Neurol, 519(15):3019-3039, 2011.

2010

Grote A, Kovacs A, Clusmann H, Becker AJ, Niehusmann P. Incidental pituicytoma after accidental head trauma - case report and review of literature. Clin Neuropathol, 29(3):127-33, 2010.

Liao Y, Deprez L, Maljevic S, Pitsch J, Claes L, Hristova D, Jordanova A, Ala-Mello S, Bellan-Koch A, Blazevic D, Schubert S, Thomas EA, Petrou S, Becker AJ, De Jonghe P, Lerche H. Molecular correlates of age-dependent seizures in inherited neonatal-infantile epilepsy. Brain, 133:1403-1414, 2010.

Niehusmann P, Bien CG, Drexler JF, Grote A, Schoch S, Becker AJ. Presence of human herpes virus-6 DNA in temporal lobe epilepsy brain tissue of patients with history of encephalitis but not other pathologies. Epilepsia, 51(12):2478-2483, 2010.

2009

Bien CG, Szinay M, Wagner J, Clusmann H, Becker AJ, Urbach H. Characteristics and surgical outcomes of patients with refractory magnetic resonance imaging-negative epilepsies. Arch Neurol, 66(12):1491-1499, 2009.

Blümcke I, Kistner I, Clusmann H, Schramm J, Becker AJ, Elger C, Bien CG, Merschhemke M, Meencke HJ, Lehmann T, Buchfelder M, Weigel D, Buslei R, Stefan H, Pauli E, Hildebrandt M. Towards a clinico-pathological classification of granule cell dispersion in human mesial temporal lobe epilepsies. Acta Neuropathol, 117(5):535-544, 2009.

Campos AR, Clusmann H, von Lehe M, Niehusmann P, Becker AJ, Schramm J, Urbach H. Simple and Complex Dysembryoplastic Neuroepithelial Tumors (DNT): clinical profile, MRI and histopathology. Neuroradiology, 51(7):433-443, 2009.

ElSharawy A, Hundrieser B, Brosch M, Wittig M, Huse K, Platzer M, Becker AJ, Simon M, Rosenstiel P, Schreiber S, Krawczak M, Hampe J. Systematic evaluation of the effect of common SNPs on pre-mRNA splicing. Hum Mutat, 30(4):625-632, 2009.

Faber-Zuschratter H, Hüttmann K, Steinhäuser C, Becker A, Schramm J, Okafo U, Shanley D, Yilmazer-Hanke DM. Ultrastructural and functional characterization of satellitosis in the human lateral amygdala associated with Ammon's horn sclerosis. Acta Neuropathol, 117(5):545-555, 2009.

Lugnier C, Majores M, Fassunke J, Pernhorst K, Niehusmann P, Simon M, Nellist M, Schoch S, Becker A. Hamartin variants frequent in focal dysplasias and cortical tubers reveal reduced tuberin binding and aberrant subcellular distribution in vitro. J Neuropathol Exp Neurol, 68(10):1136-1146, 2009.

Marcelin B, Chauvière L, Becker A, Migliore M, Esclapez M, Bernard C. h channel-dependent deficit of theta oscillation resonance and phase shift in temporal lobe epilepsy. Neurobiol Dis, 33(3):436-447, 2009.

Mittelsteadt T, Seifert G, Alvárez-Barón E, Steinhäuser C, Becker AJ, Schoch S. Differential mRNA expression patterns of the synaptotagmin gene family in the rodent brain. J Comp Neurol, 512(4):514-528, 2009.

Schönberger A, Niehusmann P, Urbach H, Majores M, Grote A, Holthausen H, Blümcke I, Deckert M, Becker AJ. Increased Frequency of Distinct TSC2 Allelic Variants in FCDs with Balloon Cells and Mineralization. Neuropathology, 5:559-565, 2009.

Schwab N, Bien CG, Waschbisch A, Becker A, Vince GH, Dornmair K, Wiendl H. CD8+ T cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery. Brain, 132(5):1236-1246, 2009.

Snoei, J, Urbach H, Engels G, Fassunke J, von Lehe M, Becker AJ, Majores M. Genetic alterations of protein-o-mannosyltransferase-1 in glioneuronal and glial brain tumors with subarachnoid spread. Neuropathology. 29(2):116-124, 2009.

2008

Alvarez-Barón E, Bien CG, Schramm J, Elger CE, Becker AJ, Schoch S. Autoantibodies to Munc18, cerebral plasma cells and B-lymphocytes in Rasmussen encephalitis. Epilepsy Res, 80(1):93-97, 2008.

Becker AJ, Pitsch J, Sochivko D, Opitz T, Staniek M, Chen CC, Campbell KP, Schoch S, Yaari Y, Beck H. Transcriptional upregulation of CaV3.2 mediates epileptogenesis in the pilocarpine epilepsy model. J Neurosci, 28(49):13341-13353, 2008.

Fassunke J, Majores M, Tresch A, Niehusmann P, Grote A, Schoch S, Becker AJ. Array analysis of epilepsy-associated gangliogliomas reveals expression patterns related to aberrant development of neuronal precursors. Brain, 131:3034-3050, 2008.

Hoischen A, Ehrler M, Fassunke J, Simon M, Baudis M, Landwehr C, Raldwimmer B, Lichter B, Schramm J, Becker AJ, Weber RG. Comprehensive characterization of genomic aberrations in gangliogliomas by comparative genomic hybridization (CGH), array-based CGH and interphase-FISH. Brain Pathol, 18(3):326-337, 2008.

Majores M, von Lehe M, Fassunke J, Schramm J, Becker AJ, Simon M. Tumor recurrence and malignant progression of gangliogliomas. Cancer, 113(12):3355-3363, 2008.

2007

Aronica E, Boer K, Becker A, Redeker S, Spliet WGM, van Rijen PC, Wittink F, Breit T, Wadman WJ, Gorter JA. Gene expression profile analysis of epilepsy-associated gangliogliomas. Neuroscience, 151(1): 272-292, 2007.

Bien CG, Urbach H, Schramm J, Soeder BM, Becker AJ, Voltz R, Vincent A, Elger CE. Limbic encephalitis as a precipitating event in adult-onset temporal lobe epilepsy. Neurology, 18;69(12):1236-1244, 2007.

Blümcke I, Pauli E, Clusmann H, Schramm J, Becker A, Elger C, Merschhemke M, Meencke HJ, Lehmann T, von Deimling A, Scheiwe C, Zentner J, Volk B, Romstock J, Stefan H, Hildebrandt M. A new clinico-pathological classification system for mesial temporal sclerosis. Acta Neuropathol, 113(3):235-244, 2007.

Kirschstein T, Bauer M, Müller L, Rüschenschmidt C, Chen J, Reitze M, Becker AJ, Schoch S, Beck H. Loss of metabotropic glutamate receptor-dependent LTD via downregulation of mGluR5 following status epilepticus. J Neurosci, 27(29):7696-7704, 2007.

Kral T, von Lehe M, Podlogar M, Clusmann H, Sussmann P, Kurthen M, Becker A, Urbach H, Schramm J. Focal cortical dysplasia: Long-term seizure outcome after surgical treatment. J Neurol Neurosurg Psychiatry, 78(8): 853-856, 2007.

Pitsch J, Schoch S, Gueler N, Flor PJ, van der Putten H, Becker AJ. Functional role of mGluR1 and mGluR4 in pilocarpine induced temporal lobe epilepsy. Neurobiol Dis, 26(3), 623-633, 2007.

Schick V, Majores M, Engels G, Hartmann W, Elger CE, Schramm J, Schoch S, Becker AJ. Differential Pi3K-pathway activation in cortical tubers and focal cortical dysplasias with balloon cells. Brain Pathol, 17(2):165-173, 2007.

Schick V, Majores M, Koch A, Elger CE, Schramm J, Urbach H, Becker AJ. Alterations of phosphatidylinositol 3-kinase pathway components in epilepsy associated glioneuronal lesions. Epilepsia, 48 Suppl 5:65-73, 2007.

Schick V, Majores M, Fassunke J, Engels G, Simon M, Elger CE, Becker AJ. Mutational and expression analysis of CDK1, cyclinA2 and cyclinB1 in epilepsy-associated glioneuronal lesions. Neuropathol Appl Neurobiol, 33(2):152-162, 2007

Stenzel W, Franitza M, Becker AJ, Montesinos-Rongen M, Lohr M, Lee JY, Rohn G, Miletic H, Deckert M. A 30-year-old patient with tuberous sclerosis. Brain Pathol, 17(3):333-334, 2007.

Urbach H, Binder D, von Lehe M, Podlogar M, Bien CG, Becker A, Schramm J, Kral T, Clusmann H. Correlation of MRI and histopathology in epileptogenic parietal and occipital lobe lesions. Seizure, 16(7):608-614, 2007.

Stuer C, Vilz B, Majores M, Becker A, Schramm J, Simon M. Frequent recurrence and progression in pilocytic astrocytoma in adults. Cancer, 110(12):2799-2808, 2007.

Yilmazer-Hanke DM, Faber-Zuschratter H, Blümcke I, Bickel M, Becker A, Mawrin C, Schramm J. Axo-somatic inhibition of projection neurons in the lateral nucleus of amygdala in human temporal lobe epilepsy: an ultrastructural study. Exp Brain Res, 177:384-399, 2007.

Weber RG, Hoischen A, Ehrler M, Zipper P, Kaulich K, Blaschke B, Becker AJ, Weber-Mangal S, Jauch A, Radlwimmer B, Schramm J, Wiestler OD, Lichter P, Reifenberger G. Frequent loss of chromosome 9, homozygous CDKN2A/p14ARF/CDKN2B deletion and low TSC1 mRNA expression in pleomorphic xanthoastrocytomas. Oncogene, 26(7):1088-1097, 2007.

2006

Baars C, Löscher W, Leeb T, Becker A, Potschka H. Polymorphic variants of the multidrug resistance gene Mdr1a and response to antiepileptic drug treatment in the kindling model of epilepsy. Eur J Pharmacol, 550:54-61, 2006.

Dupont P, Van Paesschen W, Palmini A, Ambayi R, Van Loon J, Goffin J, Weckhuysen S, Sunaert S, Thomas B, Demaerel P, Sciot R, Becker AJ, H. Vanbilloen H, Mortelmans L, Van Laere K. Ictal perfusion patterns associated with single MR-visible focal dysplastic lesions: implications for the non-invasive delineation of the epileptogenic zone. Epilepsia, 47(9):1550-1557, 2006.

ElSharawy A, Manaster C, Teuber M, Rosenstiel P, Kwiatkowski R, Huse K, Platzer M, Becker A, Nürnberg P, Schreiber S, Hampe J. SNPSplicer - Systematic analysis of SNP-dependent splicing in genotyped cDNAs. Hum Mutat, 27:1129-1134, 2006.

Franz H, Ullmann C, Becker A, Ryan M, Bahn S, Arendt T, Simon M, Pääbo S, Khaitovich P. Systematic analysis of gene expression in human brains before and after death. Genome Biology, 6(13):R112, 2006.

Hamacher M, Apweiler R, Arnold G, Becker A, Bluggel M, Carrette O, Colvis C, Dunn MJ, Frohlich T, Fountoulakis M, van Hall A, Herberg F, Ji J, Kretzschmar H, Lewczuk P, Lubec G, Marcus K, Martens L, Palacios Bustamante N, Park YM, Pennington SR, Robben J, Stuhler K, Reidegeld KA, Riederer P, Rossier J, Sanchez JC, Schrader M, Stephan C, Tagle D, Thiele H, Wang J, Wiltfang J, Yoo JS, Zhang C, Klose J, Meyer HE. HUPO Brain Proteome Project: summary of the pilot phase and introduction of a comprehensive data reprocessing strategy. Proteomics, 6(18):4890-4898, 2006.

Rüschenschmidt C, Chen J, Becker A, Riazanski V, Beck H. Functional properties and oxidative modulation of A-type K+ currents in hippocampal granule cells of control and chronically epileptic rats. Eur J Neurosci, 23(3):675-685, 2006.

Schick, V, Majores M, Engels G, Spitoni S, Koch A, Elger CE, Simon M, Knobbe C, Blümcke I, Becker AJ. Activation of Akt independent of PTEN and CTMP tumor-suppressor gene mutations in epilepsy-associated Taylor-type focal cortical dysplasias. Acta Neuropathol, 112(6):715-725, 2006.

2005

Chen J, Larionov S, Hoerold N, Ullmann C, Elger CE, Schramm J, Becker AJ. Expression analysis of metabotropic glutamate receptors I and III in mouse strains with different susceptibility to experimental temporal lobe epilepsy. Neurosci Lett, 375(3):192-197, 2005.

Fell J, Köhling R, Grunwald T, Klaver P, Dietl T, Schaller C, Becker A, Elger CE, Fernandez G. Phase-locking characteristics of limbic P3 responses in hippocampal sclerosis. Neuroimage, 24(4):980-989, 2005.

Majores M, Blümcke I, Urbach H, Meroni A, Hans V, Holthausen H, Elger CE, Schramm J, Galli C, Spreafico R, Wiestler OD, Becker AJ. Distinct allelic variants of TSC1 and TSC2 in epilepsy-associated cortical malformations without balloon cells. J Neuropathol Exp Neurol, 64(7):629-637, 2005.

Majores M, Schick V, Engels G, Fassunke J, Elger CE, Schramm J, Blümcke I, Becker AJ. Mutational and immunohistochemical analysis of ezrin-, radixin-, moesin (ERM) molecules in epilepsy associated glioneuronal lesions. Acta Neuropathol, 110:537-546, 2005.

2004

Bernard C, Anderson A, Becker A, Poolos N, Beck H, Johnston D. Acquired dendritic channelopathy in temporal lobe epilepsy. Science, 305(5683):532-535, 2004.

Fassunke J, Blümcke I, Lahl R, Elger CE, Schramm J, Merkelbach-Bruse S, Mathiak M, Wiestler OD, Becker AJ. Chromosomal instability at loci other than TSC1 is rare in focal cortical dysplasia of Taylor's balloon cell type. Acta Neuropathol, 108(2):129-134, 2004.

Fassunke J, Majores M, Ullmann C, Elger CE, Schramm J, Wiestler OD, Becker AJ. In situ-RT and immuno-laser microdissection for mRNA analysis of individual cells isolated from epilepsy associated glioneuronal tumors. Lab Invest, 84(11): 1520-1525, 2004.

Fauser S, Becker A, Schulze-Bonhage A, Hildebrandt M, Tuxhorn I, Pannek HW, Lahl R, Schramm J, Blümcke I. CD34-immunoreactive balloon cells in cortical malformations. Acta Neuropathol, 108(4): 272-278, 2004.

Kam R, Chen J, Blümcke I, Normann S, Fassunke J, Elger CE, Schramm J, Wiestler OD, Becker AJ. The reelin pathway components disabled-1 and p35 in gangliogliomas - a mutation and expression analysis. Neuropathol Appl Neurobiol, 30: 225-232, 2004.

Rudlowski C, Moser M, Becker AJ, Rath W, Büttner R, Schröder W, Schurmann A. GLUT1 mRNA and protein expression in ovarian borderline tumors and cancer. Oncology, 66 (5):404-410, 2004.

Volk HA, Burkhardt K, Potschka H, Chen J, Becker A, Löscher W. Neuronal expression of the drug efflux transporter P-glycoprotein in the rat hippocampus after limbic seizures. Neuroscience 123(3):751-759, 2004.

2003

Becker AJ, Chen J, Zien A, Sochivko D, Normann S, Schramm J, Elger CE, Wiestler OD, Blümcke I. Correlated stage- and subfield-associated hippocampal gene expression patterns in experimental and human temporal lobe epilepsy. Eur J Neurosci 18(10):2792-2802, 2003.

Ellerkmann RE, Remy S, Chen J, Sochivko D, Elger CE, Urban BW, Becker A, Beck H. Molecular and functional changes in voltage-dependent Na+ channels following pilocarpine-induced status epilepticus in rat dentate granule cells. Neuroscience 119:323-333, 2003.

Kulla A, Burkhardt K, Meyer-Puttlitz B, Teesalu T, Asser T, Wiestler OD, Becker AJ. Analysis of the TP53 gene in laser microdissected glioblastoma vasculature. Acta Neuopathol, 105(4):328-332, 2003.

Rudlowski C, Becker AJ, Schröder W, Rath W, Büttner R, Moser M. GLUT1 messenger RNA and protein induction relates to the malignant transformation of cervical cancer. Am J Clin Pathol 120(5):691-698, 2003.

Sochivko D, Chen J, Becker A, Beck H. Blocker resistant Ca2+ currents in rat CA1 hippocampal pyramidal neurons. Neuroscience 116:629-638, 2003.

2002

Becker AJ, Chen J, Paus S, Normann S, Beck H, Elger CE, Wiestler OD, Blümcke I. Transcriptional profiling in human epilepsy: expression array and single cell real-time qRT-PCR analysis reveal distinct cellular gene regulation. Neuroreport 13:1327-1333, 2002.

Becker AJ, Klein H, Baden T, Aigner L, Normann S, Elger CE, Schramm J, Wiestler OD, Blümcke I. Mutational and expression analysis of the reelin pathway components CDK5 and doublecortin in gangliogliomas. Acta Neuropathol 104(4):403-408, 2002.

Becker AJ, Urbach H, Scheffler B, Baden T, Normann S, Lahl R, Pannek HW, Tuxhorn I, Elger CE, Schramm J, Wiestler OD, Blümcke I. Focal cortical dysplasia of Taylor's balloon cell type: mutational analysis of the TSC1 gene indicates a pathogenic relationship to tuberous sclerosis. Ann Neurol 52:29-37, 2002.

Su H, Sochivko D, Becker A, Chen J, Jiang Y, Yaari Y, Beck H. Upregulation of a T-type Ca2+ channel causes a long-lasting modification of neuronal firing mode after status epilepticus. J Neurosci 22:3645-3655, 2002.

Varlamov DA, Kudin AP, Vielhaber S, Schröder R, Sassen R, Becker A, Kunz D, Haug K, Rebstock J, Heils A, Elger CE, Kunz WS. Metabolic consequences of a novel missense mutation of the mtDNA CO I gene. Hum Mol Genet 11:1797-1805, 2002.

2001

Becker AJ, Löbach M, Klein H, Normann S, Nöthen MM, von Deimling A, Mizuguchi M, Elger CE, Schramm J, Wiestler OD, Blümcke I. Mutational analysis of TSC1 and TSC2 genes in gangliogliomas. Neuropathol Appl Neurobiol, 27:105-114, 2001.

Blümcke I, Becker AJ, Normann S, Hans V, Riederer BM, Krajewski S, Wiestler OD, Reifenberger G. Distinct expression pattern of microtubule-associated protein-2 in human oligodendrogliomas and glial precursor cells. J Neuropathol Exp Neurol 60:984-993, 2001.

Chen J, Sochivko D, Beck H, Marechal D, Wiestler OD, Becker AJ. Activity-induced expression of common reference genes in individual CNS neurons. Lab Invest 81(6):913-916, 2001.

Dettmeyer R, Driever F, Becker A, Wiestler OD, Madea B. Fatal myeloencephalopathy due to accidental intrathecal vincristin administration - a report of two cases. J Forensic Sci 122 (1):60-64, 2001.

Riazanski V, Becker A, Chen J, Sochivko D, Lie A, Wiestler OD, Elger CE, Beck H.Functionaland molecular analysis of transient voltage-dependent K+ currents in rat hippocampal granulecells. J Physiol 537:391-406, 2001.

Rudlowski C, Rath W, Becker AJ, Wiestler OD, Büttner R. Trastuzumab and breast cancer. New Engl J Med 345 (13):997-998, 2001.

2000

Blümcke I, Becker A, Klein C, Scheiwe C, Lie AA, Beck H, Waha A, Friedel M, Kuhn R, Emson P, Elger C, Wiestler OD. Temporal lobe epilepsy associated up-regulation of metabotropic glutamate receptors: correlated changes in mGluR1 mRNA and protein expression in experimental animals and human patients. J Neuropathol Exp Neurol 59:1-10, 2000.

Busjahn A, Li GH, Faulhaber HD, Rosenthal M, Becker A, Jeschke E, Schuster H, Timmermann B, Hoehe MR, Luft FC. beta-2 Adrenergic Receptor Gene Variations, Blood Pressure, and Heart Size in Normal Twins. Hypertension 35:555-560, 2000.

Lie AA, Becker A, Behle K, Beck H, Malitschek B, Conn PJ, Kuhn R, Nitsch R, Plaschke M, Schramm J, Elger CE, Wiestler OD, Blümcke I. Up-regulation of the metabotropic glutamate receptor mGluR4 in hippocampal neurons with reduced seizure vulnerability. Ann Neurol 47:26-35, 2000.

1999

Becker AJ, Gillardon F, Blümcke I, Langendörfer D, Beck H, Wiestler OD. Differential regulation of apoptosis-related genes in resistant and vulnerable subfields of the rat epileptic hippocampus. Brain Res Mol Brain Res 67:172-176, 1999.

1997

Becker AJ, Busjahn A, Faulhaber HD, Bähring S, Robertson J, Schuster H, Luft FC. Twin zygosity. Automated determination with microsatellites. J Reprod Med 42:260-266, 1997.

Busjahn A, Knoblauch H, Knoblauch M, Bohlender J, Menz M, Faulhaber HD, Becker A, Schuster H, Luft FC. Angiotensin-converting enzyme and angiotensinogen gene polymorphisms, plasma levels, cardiac dimensions. A twin study. Hypertension 29:165-170, 1997.

Übersichtsarbeiten

2009

Battaglia G, Becker AJ, LoTurco J, Represa A, Baraban SC, Roper SN, Vezzani A. Basic Mechanisms in MCD in Animal Models. Epileptic Disorders, 11:802-808, 2009.

2007

Majores M, Lie A, Schoch S, Becker AJ. Molecular neuropathology of temporal lobe epilepsy: complementary approaches in animal models and human disease tissue. Epilepsia, 48 Suppl 2:4-12, 2007.

2006

Becker AJ. Neuropathology and classification of cortical malformations - where do they develop? Epilepsia, 47:949-951, 2006.

Becker AJ, Blümcke I, Urbach H, Hans V, Majores M. Molecular neuropathology of epilepsy-associated glioneuronal malformations. J Neuropathol Exp Neurol, 65(2):99-108, 2006.

Crino PB, Becker AJ. Gene profiling in temporal lobe epilepsy tissue and dysplastic lesions. Epilepsia, 47(10):1608-1616, 2006.

2004

Majores M, Eils J, Wiestler OD, Becker AJ. Molecular profiling of temporal lobe epilepsy: comparison of data from human tissue samples and animal models. Epilepsy Res, 60:173-178, 2004.

Schulte JH, Pitsch J, Becker AJ. Functional genomics and target gene validation in experimental and human disease. Drug Discovery Today: Technologies, 1(2):105-111, 2004.

2003

Urbach H, Blümcke I, Becker A, Solymosi L. Störungen der kortikalen Entwicklung: Bildgebung und Klassifizierung. Klin Neuroradiol 13:163-172, 2003.

2002

Becker AJ, Wiestler OD, Blümcke I. Functional genomics in experimental and human temporal lobe epilepsy: powerful new tools to identify molecular disease mechanisms of hippocampal damage. Prog Brain Res 135:161-173, 2002.

Buchbeiträge 2012

Becker AJ. Epilepsy-associated gangliogliomas: identification of genes with altered expression. Tumors of the Central Nervous System. Volume 5, Hayat MA (ed.). 2012, Volume 5, Part 5, 267-273 Springer Press.

2007

Becker AJ, Wiestler OD, Figarella-Branger D, Blümcke I. Ganglioglioma and Gangliocytoma. In: WHO Classification of Tumours of the Central Nervous System, Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, (eds.), pp. 103-105, IARC: Lyon, 2007.

Nakazato Y, Figarella-Branger D, Becker AJ, Scheithauer BW, Rosenblum MK. Papillary glioneuronal tumour. In: WHO Classification of Tumours of the Central Nervous System, Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, (eds.), pp. 103-105, IARC: Lyon, 2007.

2002

Seifert G, Becker AJ, Steinhäuser C. Combining patch-clamp techniques with RT-PCR. In: Advanced techniques for patch clamp analysis. Walz W, Boulton A, Baker G, eds. Humana Press, 301-330, 2002.

 
Unsere Webseite verwendet Cookies.

Bei Cookies handelt es sich um Textdateien, die im Internetbrowser bzw. vom Internetbrowser auf dem Computersystem des Nutzers gespeichert werden. Ruft ein Nutzer eine Website auf, so kann ein Cookie auf dem Betriebssystem des Nutzers gespeichert werden. Dieser Cookie enthält eine charakteristische Zeichenfolge, die eine eindeutige Identifizierung des Browsers beim erneuten Aufrufen der Website ermöglicht. Wir setzen Cookies ein, um unsere Website nutzerfreundlicher zu gestalten. Einige Elemente unserer Internetseite erfordern es, dass der aufrufende Browser auch nach einem Seitenwechsel identifiziert werden kann.

Unsere Webseite verwendet Cookies.

Bei Cookies handelt es sich um Textdateien, die im Internetbrowser bzw. vom Internetbrowser auf dem Computersystem des Nutzers gespeichert werden. Ruft ein Nutzer eine Website auf, so kann ein Cookie auf dem Betriebssystem des Nutzers gespeichert werden. Dieser Cookie enthält eine charakteristische Zeichenfolge, die eine eindeutige Identifizierung des Browsers beim erneuten Aufrufen der Website ermöglicht. Wir setzen Cookies ein, um unsere Website nutzerfreundlicher zu gestalten. Einige Elemente unserer Internetseite erfordern es, dass der aufrufende Browser auch nach einem Seitenwechsel identifiziert werden kann.

Ihre Cookie-Einstellungen wurden gespeichert.